New Sepsis Definitions Published in JAMA and Highlighted at Congress


We are sharing an interesting article which was published today on the Society for Critical Care Medicine website, about the new sepsis definitions published in JAMA recently.

New Sepsis Definitions Published in JAMA and Highlighted at Congress

Published on Society for Critical Care Medicine website, March 2, 2016.

In a series of articles published last month in JAMA and released during the 45th Critical Care Congress, an international task force updated definitions of sepsis and septic shock. The group’s recommendations not only advance new definitions for sepsis and septic shock, but also offer clinical guidance to help physicians more quickly identify patients with or at risk of developing sepsis.

At present, The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3), has more than 560,000 views, making it one of the best viewed JAMA articles of all time.

Accompanying articles by Seymour et al and Angus et al published in Critical Care Medicine also present a conceptual framework to help patients, clinicians, researchers and hospitals apply the new definitions. The Society has also released a podcast SCCM Pod-311 New Sepsis Definitions: An In-Depth Interview with Craig Coopersmith, (you can listen to it here: podcast to help give context to the new definitions.

“This is an incredibly exciting time in the field of sepsis,” said Craig M. Coopersmith, MD, FCCM, a task force member and immediate past president of the Society. “Driven by a combination of data analysis on well over one million patients as well as expert consensus, these new definitions provide a real step forward.”

The task force definitions were directly informed by research out of the Clinical Research, Investigation, and Systems Modeling of Acute illness (CRISMA) Center at the Pitt School of Medicine and were funded in part by grants from the National Institutes of Health. They were sponsored by more than 30 organizations representing a variety of professionals who manage and diagnose sepsis.

Visit for a complete list of resources and articles. Also, make sure to read this informative Medscape article centered on the updated definitions of sepsis and septic shock.

Keep the discussion on Twitter going by using #SepsisRedefined. Join the #SepsisRedefined conversation group for updates on upcoming Twitter Chats on this topic.